Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-07-23 · biorxiv
· doi:10.64898/2026.07.22.739977
Mihalas, B. P.; Lin, D.; Bustamante, S.; Pickford, R.; Frost, E. R.; Vuyyuru, A.; Wong, D. Y.; Bertoldo, M. J.; Wu, L. E.; Gilchrist, R. B.
The age-related decline in oocyte nicotinamide adenine dinucleotide (NAD) is associated with reduced developmental potential and female infertility. Despite the extraordinary longevity of the female germline, the mechanism for maintaining oocyte NAD remains unresolved. Here, we used stable isotope tracing to identify a new mechanism for shared, intercellular NAD biosynthesis, whereby somatic-germ…
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bioRxiv (preprint)
· 2026-07-23 · biorxiv
· doi:10.64898/2026.07.16.739045
Repges, E.; Schinhammer, S.; Al-Kassou, B.; Yousif, A.; Schott, A.; Wesendonk, D.; Bartsch, B.; Jamin, R. N.; Barthen, M.; Shamekhi, J.; Bakhtiary, F.; Baldus, S.; Kelm, M.; Oldenburg, J.; Czogalla-Nitsche, K. J.; Nickenig, G.; Zimmer, S.; Al Zaidi, M.
Background: Calcific aortic valve stenosis (AS) is the most common valvular heart disease in the aging population and lacks effective pharmacological therapy. Oxidative stress is a key feature of valvular remodeling, yet the mechanisms linking oxidative injury to calcification remain unclear. Ferroptosis, a lipid peroxidation-driven form of regulated cell death, has emerged as a key mediator of o…
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bioRxiv (preprint)
· 2026-07-23 · biorxiv
· doi:10.64898/2026.07.22.740085
Farr, A. S.; Orr, J. C.; Ahmed, B. M.; Hascher, L.; Brooks, T.; Hynds, R. E.
Age is a principal risk factor for chronic respiratory diseases. During aging, the airway epithelium undergoes structural and functional changes, including a reduced regenerative capacity. Basal cells act as stem/progenitor cells within the airway epithelium and are known to acquire age-dependent intrinsic defects, such as genomic mutations, transcriptomic changes and declining stem cell potentia…
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JPRAS open
· 2026 Sep · pubmed
· doi:10.1016/j.jpra.2026.05.041
Bohórquez JMC, Wan J, Wong IKJ, Green JB
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Rejuvenation research
· 2026 Jun 8 · pubmed
· doi:10.1177/15491684261449703
Devi R, Shukla D, Kumar V, Upadhayay S
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Rejuvenation research
· 2026 Jun 17 · pubmed
· doi:10.1177/15491684261462406
Zhang Y, Gao Y, Luo A, Liang A
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Rejuvenation research
· 2026 Jun 17 · pubmed
· doi:10.1177/15491684261462413
Chan AHY, Beyene K, Lai B, Kim S
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Rejuvenation research
· 2026 Jul 9 · pubmed
· doi:10.1177/15491684261460820
Hao Z, Meng T, Li S, Bu Y
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Aging
· 2026 Jul 8 · pubmed
· doi:10.18632/aging.206404
Chang WT, Shih JY, Lin YW, Huang TL
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Aging
· 2026 Jul 8 · pubmed
· doi:10.18632/aging.206398
Lorente ABL, Vazquez S, Iwasaki K, Adebayo A
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Nature aging
· 2026 Jul 24 · pubmed
· doi:10.1038/s43587-026-01169-0
Calubag MF, Ademi I, Green CL, Manchanayake DNH
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Scientific reports
· 2026 Jul 24 · pubmed
· doi:10.1038/s41598-026-60835-w
Zushi K, Seki M, Mizuochi R, Shitamitsu K
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AJNR. American journal of neuroradiology
· 2026 Jul 24 · pubmed
· doi:10.3174/ajnr.A9546
Lee SH, Jung W, Park M, Cho H
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Journal of voice : official journal of the Voice Foundation
· 2026 Jul 24 · pubmed
· doi:10.1016/j.jvoice.2026.06.052
ElAdawy AN, Emam AM, Tamam A, Mostafa E
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BMJ open
· 2026 Jul 24 · pubmed
· doi:10.1136/bmjopen-2026-116456
Dahel H, Williamson D, Li Q, Dumais C