Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-07-24 · biorxiv
· doi:10.64898/2026.07.23.740245
Eskiw, C. H.; Martinez, V.; Lubachowski, M.; Gillespie, Z. E.; Fleming, M.; Harkness, T. A. A.
The premature aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) results from the accumulation of progerin, a cytotoxic protein generated from a point mutation in the Lamin A/C gene, in the nuclear lamina. Upon the proper stimulation, cells degrade progerin, reversing cellular HGPS phenotypes; however, there is still a gap in our knowledge concerning which pathways are mediating progerin d…
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bioRxiv (preprint)
· 2026-07-24 · biorxiv
· doi:10.64898/2026.07.23.740352
Shao, J.; Bao, X.; Yaman, I.; Zheng, Y.; Wang, J.; Li, J.; Yang, T.; Jian, J.; Li, J.; Blackshaw, S.; Bharti, K.; Clarke, M.; Stambolian, D. E.; Sung, C.-H.; Zheng, J. J.; Ortolan, D.; Zhang, S. X.; Sharma, R.; Scheuermann, R. H.; Pankajam, A. V.; Ghobashi, A. H.; Ma, A.; Ma, Q.; Futey, M.; Villani, A.-C.; Stout, J. T.; DeAngelis, M. M.; Chen, H.; Li, Y.; Chen, R.
The retinal pigment epithelium and choroid are critical for supporting the function and maintaining the homeostasis of the outer retina, and their dysfunction underlies a range of inherited and complex ocular diseases. To comprehensively characterize the cellular, transcriptomic, and epigenomic heterogeneity and dynamics within these tissues, we assembled an integrated multi-omics reference atlas…
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bioRxiv (preprint)
· 2026-07-24 · biorxiv
· doi:10.64898/2026.07.08.735777
Hidalgo Gil, D.; Garcia Garcia, A.; Wolf, F.; Gonzalez Anton, S.; Bosch, S.; Grigoryan, A.; Barbero, A.; Bourgine, P. E.
Differentiation programs remain incompletely understood across stem cell types, including for human bone marrow mesenchymal stromal/stem (BM-MSCs) cells, a heterogenous population orchestrating bone formation and establishing a functional hematopoietic niche in the bone marrow. BM-MSCs form and repair bone through the evolutionarily conserved process of endochondral ossification (EO), initiated b…
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JPRAS open
· 2026 Sep · pubmed
· doi:10.1016/j.jpra.2026.05.041
Bohórquez JMC, Wan J, Wong IKJ, Green JB
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Rejuvenation research
· 2026 Jun 8 · pubmed
· doi:10.1177/15491684261449703
Devi R, Shukla D, Kumar V, Upadhayay S
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Rejuvenation research
· 2026 Jun 17 · pubmed
· doi:10.1177/15491684261462406
Zhang Y, Gao Y, Luo A, Liang A
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Rejuvenation research
· 2026 Jun 17 · pubmed
· doi:10.1177/15491684261462413
Chan AHY, Beyene K, Lai B, Kim S
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Rejuvenation research
· 2026 Jul 9 · pubmed
· doi:10.1177/15491684261460820
Hao Z, Meng T, Li S, Bu Y
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Aging
· 2026 Jul 8 · pubmed
· doi:10.18632/aging.206404
Chang WT, Shih JY, Lin YW, Huang TL
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Aging
· 2026 Jul 8 · pubmed
· doi:10.18632/aging.206398
Lorente ABL, Vazquez S, Iwasaki K, Adebayo A
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Annals of surgical oncology
· 2026 Jul 26 · pubmed
· doi:10.1245/s10434-026-20293-0
Gunder MA, Badgwell BD, Kelly KJ
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Health economics
· 2026 Jul 25 · pubmed
· doi:10.1002/hec.70128
Stafford T, Zhang X, Hanewald K
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Dental materials : official publication of the Academy of Dental Materials
· 2026 Jul 25 · pubmed
· doi:10.1016/j.dental.2026.07.016
Alhotan A, Silikas N, Ibrahim YM, Al-Johani H
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Dental materials : official publication of the Academy of Dental Materials
· 2026 Jul 25 · pubmed
· doi:10.1016/j.dental.2026.07.014
Pan Y, Xu J, Cai X, Li X
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Experimental gerontology
· 2026 Jul 25 · pubmed
· doi:10.1016/j.exger.2026.113250
Ke S, Yang H, Lu W, Wu L