Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-09-10 · biorxiv
· doi:10.1101/2025.06.16.659752
Garrod-Ketchely, C.; Callender, L. A.; Schroth, J.; Littlewood, K.; Carroll, E. C.; Tamsan, D.; Tsang, V. S.; Nessel, I.; Riddell, N. E.; Chain, B.; Aksentijevic, D.; Harding, D.; Marelli-Berg, F. M.; Bystrom, J.; Pereira Da Costa, M.; Carrascal-Minino, A.; Keeling, G. P.; Pham, T. T.; Sunassee, K.; De Rosales, R. T.; Terry, S. Y.; Pattrick, M.; Sutcliffe, C.; Worthington, A.; Hood, G.; Finer, S.; Henson, S. M.
Ageing is accompanied by progressive remodelling of the immune system, but chronic metabolic disease may accelerate this process and drive qualitatively distinct forms of immune dysfunction. Here, we used type 2 diabetes (T2D) as a model of unhealthy immune ageing to identify a distinct population of CD8 TEMRA cells that accumulates in older individuals with T2D. These cells were highly different…
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bioRxiv (preprint)
· 2026-09-10 · biorxiv
· doi:10.1101/2025.09.01.672798
Xu, C. K.; Meisl, G.; Moshkov, N.; Schmacke, N. A.; Goda, K.; Shkarin, A.; Schlögel, M. F.; Diebold, S.; Schweitzer, C.; Ekici, A.; Knowles, T. P.; Theis, F. J.; Mazutis, L.; Guck, J.
Understanding sequence-phenotype relationships in biology requires large-scale datasets that provide one-to-one mapping of sequence to phenotype. Here, we address this challenge by introducing multimodal droplet barcoding, enabling individual microfluidic droplets to be tracked across both optical and sequencing measurements. We demonstrate the power of this approach through multimodal single-cel…
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bioRxiv (preprint)
· 2026-09-10 · biorxiv
· doi:10.64898/2026.09.06.749697
Igiebor, F.; Wuerthner, L.; Stamm, F.; Haque, S.; Havlicek, O.; Schmidt, J.; Cetiner, M.; Zubcic, I.; Heliel, O.; Saunders, L. M.; Graf, I. R.; van Gelderen, K.
Phytochrome B is a crucial red and far-red light sensor, which controls plant development and environmental responses to light and temperature. In the nucleus, phyB forms phase separated condensates, also called photobodies, consisting of various transcriptional regulators and transcription factors. phyB photobodies can form or disperse depending on the amount of light, the light quality, or ambi…
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bioRxiv (preprint)
· 2026-09-10 · biorxiv
· doi:10.64898/2026.03.31.715748
Sun, H.; Kahnert, K.; Hansen, J. N.; Leineweber, W. D.; Li, M.; Feng, W.; Ballllosera Navarro, F.; Axelsson, U.; Ouyang, W.; Lundberg, E.
The spatial organization of proteins within cells governs virtually all cellular functions, yet current imaging can simultaneously visualize only tens of proteins, orders of magnitude below the thousands populating a single human cell. Here we present ProtiCelli, a deep generative model that simulates microscopy images for 12,800 human proteins from just three cellular landmark stains. Trained on…
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The Journal of prosthetic dentistry
· 2026 Sep 11 · pubmed
· doi:10.1016/j.prosdent.2026.08.002
Kim D, Chang J, Bhatia H, Takoudis C
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Trends in molecular medicine
· 2026 Sep 11 · pubmed
· doi:10.1016/j.molmed.2026.08.003
Shim HS, DePinho RA
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Environmental research
· 2026 Sep 11 · pubmed
· doi:10.1016/j.envres.2026.125665
Jin R, Wang Y, Kwan KY, Sharifinia M
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Neurotoxicology
· 2026 Sep 11 · pubmed
· doi:10.1016/j.neuro.2026.103574
Chang JE, Joo H, Lee EH, Oh SJ
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Transplantation and cellular therapy
· 2026 Sep 11 · pubmed
· doi:10.1016/j.jtct.2026.09.011
Bejarano-García JA, Nufer M, Caracuel R, Caballero-Velázquez T
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Geriatric nursing (New York, N.Y.)
· 2026 Sep 11 · pubmed
· doi:10.1016/j.gerinurse.2026.104346
Qiu Y, Li R
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Science advances
· 2026 Sep 11 · pubmed
· doi:10.1126/sciadv.adz3976
Kramer L, Dai Z, Corbin J, Ringquist R
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Neotropical entomology
· 2026 Sep 11 · pubmed
· doi:10.1007/s13744-026-01435-1
Di Bello MM, de Souza BHS, Costa EN, Nogueira L
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GeroScience
· 2026 Sep 11 · pubmed
· doi:10.1007/s11357-026-02501-7
Seidu NM, Rydén L, Skoog J, Samuelsson J
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Circulation. Cardiovascular interventions
· 2026 Sep 11 · pubmed
· doi:10.1161/CIRCINTERVENTIONS.126.017207
Alkhatib R, Hatab T, Alfaraidhy M, Karthikeyan N
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Gut
· 2026 Sep 11 · pubmed
· doi:10.1136/gutjnl-2026-339264
Guicciardi ME, Pistorio V, Soret PA, Steunou V