Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-09-16 · biorxiv
· doi:10.64898/2026.09.11.751025
Gaye, A.; Oliver, A. F.; Lindsey, M. L.; Gonzalez, G.
Background Galectins regulate inflammation, fibrosis, immunity, and vascular remodeling. Although galectin-3 has been widely studied in cardiovascular disease, the relative contributions of other galectins to blood pressure regulation remain unclear. We systematically evaluated associations between galectin gene expression and systolic blood pressure (SBP) in African Americans. Methods Whole-bloo…
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bioRxiv (preprint)
· 2026-09-16 · biorxiv
· doi:10.64898/2026.09.10.750646
Nah, J.; Sun, A.; Yadav, A.; Scheinfeld, A.; Azad, T.; Rose, S.; Becher, B.; Smithy, J. W.; Postow, M. A.; Ariyan, C. E.; Pritykin, Y.; Brown, C.
Blockade of inhibitory PD-1 signaling on T cells is a cornerstone of cancer immunotherapy, with current strategies targeting PD-1 or its ligand PD-L1. However, PD-1 engages an alternative ligand, PD-L2, whose role in tumor immunity remains poorly defined. Here, we show that PD-L2 is upregulated on intratumoral CCR7+ conventional dendritic cells (cDCs) in both mouse and human melanoma. Using genet…
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bioRxiv (preprint)
· 2026-09-16 · biorxiv
· doi:10.64898/2026.09.10.750782
wu, q.; liu, l.; jiang, m. s.
Purpose Tumors are often framed as unresolved wounds, but the extent to which independently defined physiological repair programs are recontextualized across cancers remains uncertain. Methods We derived five lineage-associated modules and a composite score from 58,823 cells in a longitudinal human skin-wound cohort before examining tumors. Frozen modules were evaluated in paired hepatocellular c…
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bioRxiv (preprint)
· 2026-09-16 · biorxiv
· doi:10.1101/2025.04.09.648041
Wolf, S. E.; Babayan, S. A.; Marioni, R. A.; Chandra, T.; Horvath, S.; Little, T. J.; Pedersen, A. B.
Environmental stressors are expected to accelerate senescence but demonstrating this requires both a measure of senescence and knowledge of chronological age - data rarely available for most wild animals. Here, we constructed a DNA methylation-based epigenetic clock for the wood mouse (Apodemus sylvaticus) using known-aged laboratory individuals and applied it to a wild population of unknown ages…
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iScience
· 2026 Sep 18 · pubmed
· doi:10.1016/j.isci.2026.117396
Zhang M, Wang H, Liu H, Zhao D
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Journal of the American Geriatrics Society
· 2026 Sep 17 · pubmed
· doi:10.1111/jgs.70722
McGough K, Jones A, Zweig SC, Mehr DR
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Dental materials : official publication of the Academy of Dental Materials
· 2026 Sep 17 · pubmed
· doi:10.1016/j.dental.2026.09.006
Dimitriadi M, Petropoulou A, Zinelis S, Eliades G
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Annual review of pathology
· 2026 Sep 17 · pubmed
· doi:10.1146/annurev-pathmechdis-042624-113746
Um J, Adelman JW, Pollina EA
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Journal of dairy science
· 2026 Sep 17 · pubmed
· doi:10.3168/jds.2026-28690
Silva LH, Gong Y, Cabrera VE
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Journal of dairy science
· 2026 Sep 17 · pubmed
· doi:10.3168/jds.2026-28835
Lindner EE, Miller-Cushon EK
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Heart rhythm
· 2026 Sep 17 · pubmed
· doi:10.1016/j.hrthm.2026.09.016
Ip JE, Cheung JW, Liu CF, Thomas G
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Experimental gerontology
· 2026 Sep 17 · pubmed
· doi:10.1016/j.exger.2026.113330
Xu X, Qin A, Han L, Meng F
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Free radical biology & medicine
· 2026 Sep 17 · pubmed
· doi:10.1016/j.freeradbiomed.2026.09.016
Luo Y, Zhang Y, Song Y, Li X
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Neuroscience and biobehavioral reviews
· 2026 Sep 17 · pubmed
· doi:10.1016/j.neubiorev.2026.106983
Kang JI, Il Park C, Kim SJ
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Clinical & experimental metastasis
· 2026 Sep 17 · pubmed
· doi:10.1007/s10585-026-10431-z
Guo M, Xu B, Xu R, Miao Z