Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-09-17 · biorxiv
· doi:10.64898/2026.09.14.751521
Moussaoui, S.; Gimenez, M. C.; Paixao, A.; Boulianne, M.; Cabrini, M.; Kanbar, A.; Okhunjonov, A.; Arnillas, C. A.; Terebiznik, M.
Aspergillus fumigatus is the leading cause of aspergillosis in immunocompromised individuals. Because A. fumigatus hyphae rapidly outgrow macrophages, they are generally thought to evade macrophage-mediated control once they exceed the size limits of phagocytosis, enabling invasive growth within host tissues. Here, we show that macrophages circumvent this limitation by capturing hyphal tips withi…
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bioRxiv (preprint)
· 2026-09-17 · biorxiv
· doi:10.64898/2026.09.14.750894
Ricol, M.; Dieryckx, C.; Callies, C.; Vadon-Le Goff, S.; VINCOURT, J.-B.; Moali, C.; See, V.
Collagen biosynthesis is a complex multistep process, essential for functional tissue formation and repair. It is highly active during embryogenesis and wound healing, leading to physiological fibrogenesis, while its dysregulation induces pathologies affecting connective tissues, namely fibrosis. There are several key cellular microenvironmental factors regulating collagen biosynthesis, including…
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bioRxiv (preprint)
· 2026-09-17 · biorxiv
· doi:10.64898/2026.09.15.749901
Smialkovska, V.; Dicke, A.-K.; Feldmann, A.
Distal regulatory elements (DREs), such as enhancers, can regulate genes across megabase-long distances, presumably via coming into close spatial proximity. The establishment of new transcriptional programmes during cell type transitions is associated with widespread rewiring of the spatial organisation of the genome, including gain and loss of chromatin interactions. Extensive effort has been in…
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bioRxiv (preprint)
· 2026-09-17 · biorxiv
· doi:10.64898/2026.09.15.751479
Akinmusola, R. Y.; Kon, T.; Kon-Nanjo, K.; Minhas, R.; O'Neill, P.; Jeffries, A.; Shimada, Y.; Ramsdale, M.; Kudoh, T.
The Arabian killifish (Aphaniops dispar) is an excellent model for studying human diseases such as fungal infections and cancer progression. The embryos possess a transparent chorion for live imaging and display an extended period of independent feeding (13 days post-fertilisation). They also exhibit broad thermal tolerance which enables live imaging at physiologically relevant human temperatures…
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bioRxiv (preprint)
· 2026-09-17 · biorxiv
· doi:10.64898/2026.09.11.751051
Pereira da Silva, E.; Alves, I.; Voorhees, H.; Sirish, P.; Daghbouche Rubio, N.; Martin Aragon Baudel, M.; Xiang, Y.; Navedo, M. F.; Nieves-Cintron, M.
The second messenger, cyclic adenosine monophosphate (cAMP), plays a crucial role in regulating cellular function, including in vascular smooth muscle (VSM). While extensive research has focused on the compartmentalization of cAMP signaling in various cell types, the influence of biological sex on distinct cAMP pools and their functional implications in the VSM remains largely unexplored. To addr…
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bioRxiv (preprint)
· 2026-09-17 · biorxiv
· doi:10.64898/2026.09.13.751251
Frey, T.; Vogg, H.; Ahmad, M.; Nakano, Y.; Vogel, M.; Nungess, S.; Schoppa, A.; Geiger, H.; Ignatius, A.; Riegger, J.
Cellular senescence has emerged as a key contributor to age-related skeletal deterioration; however, the defining characteristics of senescent osteoblasts remain incompletely understood, hindering efforts to identify the cellular mechanisms that drive age-associated bone loss and potential therapeutic targets. Here, we compared doxorubicin- and hydrogen peroxide-induced senescence and established…
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GeroScience
· 2026 Sep 19 · pubmed
· doi:10.1007/s11357-026-02544-w
Wei X, Shao R, Rolland Y, Vellas B
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Medicine
· 2026 Sep 18 · pubmed
· doi:10.1097/MD.0000000000050770
Li J, Cao P, Chen Y
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Medicine
· 2026 Sep 18 · pubmed
· doi:10.1097/MD.0000000000050734
Qian Y
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Journal of the American Geriatrics Society
· 2026 Sep 18 · pubmed
· doi:10.1111/jgs.70732
Pagali S, Liu X, Jia H, Fischer K
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BMC geriatrics
· 2026 Sep 18 · pubmed
· doi:10.1186/s12877-026-08260-6
Shubing F, Pengpeng W, Hongxia H, Zhenhong L
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Companion animal health and genetics
· 2026 Sep 18 · pubmed
· doi:10.1186/s40575-026-00158-1
Ferrari C, Bernini F, Marelli SP, Poli M
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Genetics, selection, evolution : GSE
· 2026 Sep 18 · pubmed
· doi:10.1186/s12711-026-01087-0
Ramos P, Tsuruta S, Garcia A, Retallick K
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Facial plastic surgery : FPS
· 2026 Sep 18 · pubmed
· doi:10.1055/a-2962-4787
D'Souza H, AlKandery M, Mandavia R
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Bone & joint open
· 2026 Sep 18 · pubmed
· doi:10.1302/2633-1462.79.BJO-2026-0178.R1
Naudie DDR, Lanting BA, Bohm E, Teeter M