La mayoría del PSOE y el Gobierno anima a Sánchez a convocar elecciones ya: “Ahora hay una oportunidad”
El adelanto es la opción más probable, pero algunos creen que antes aún habría que intentar sacar otros decretos
07:00 Europe/Madrid · ventana últimas 24 h
El adelanto es la opción más probable, pero algunos creen que antes aún habría que intentar sacar otros decretos
Enrique Santiago, portavoz parlamentario de IU, reclama la convocatoria de las generales mientras Podemos aboga por llevar antes un nuevo decreto al Congreso
Los populares, seguros de su victoria, hacen cábalas sobre el equipo que elegiría su líder. Dirigentes reconocen sus carencias en Interior y Exteriores
El partido independentista diseña la nueva hoja de ruta en base al regreso de su líder e ignora las críticas por tumbar los decretos de vivienda
Aliança Catalana se sitúa como segunda fuerza mientras Junts se hunde y Vox crece
Solo un 12% apuesta por dejar actuar al mercado y reducir impuestos y normativas
La ultraderecha seduce a las clases medias, que se sienten abandonadas por los partidos tradicionales
The man accused of trying to take over the Israel-bound jet is named as Hamam al-Hammami by several media outlets.
Western Libya’s GNU say working with Saddam Haftar ‘impossible’ as US-backed merger plan breaks down Allegations that the son of the Libyan warlord Khalifa Haftar oversaw a “terror cell” that launched drone attacks on fuel storage facilities and power stations in western Libya have upended plans for the Tripoli-based government of national unity (GNU) to continue cooperating with Haftar on a plan to unify the country. Saddam Haftar, the deputy commander of the so-called Libyan National Army (LNA), has increasingly been seen by the US as an important figure in its plans to unify Libyan…
The plane was undertaking a medical evacuation from Bermuda with six people onboard when it lost contact The US Coast Guard said late on Saturday it had found debris from a medical transport aircraft off the shore of Massachusetts’ Nantucket Island and was searching for the six people who were on board. The jet lost contact with the Federal Aviation Administration (FAA) during a flight from Bermuda to Boston on Saturday morning. In a statement to the Guardian, an FAA spokesperson said that the agency issued a search-and-rescue alert notice for a Gulfstream G-100 at about 1.20am local time…
Sunday’s poll pits the leftist incumbent Lula against the son of a former far-right president convicted of staging a coup ‘No one disrespects Our Lady’: fears for Brazil’s patron saint grip country ahead of election Shortly after his controversial speech to the United Nations general assembly in September, Donald Trump gathered a dozen like-minded Latin American leaders and boasted that rightwing candidates had won all seven presidential elections held in the region since he began his second term. “Everybody I’ve endorsed has won,” the US president said in New York to most of the leaders of…
The drug is targeted at Bundibugyo virus, which is responsible for the fast-moving outbreak and is without an approved vaccine or treatment. The trial began in July and is one of several studies launched to find some protection and another way of at least slowing the outbreak.
Malgré les éléments de preuve livrés par « Mediapart », le Rassemblement national fait bloc derrière son président dans l’espoir que l’orage passe, au risque de voir le discrédit de Jordan Bardella contaminer la candidate à la présidentielle.
Le président de gauche Lula et son rival d’extrême droite Flavio Bolsonaro sont au coude-à-coude dans les sondages avant les élections générales dimanche 4 octobre.
Depuis le démantèlement brutal de l’Usaid, des accords bilatéraux, répondant aux intérêts américains, ont remplacé l’aide humanitaire. Le refus de subventionner la promotion ou la pratique de l’avortement en est l’une des dispositions, notamment en Afrique.
Les responsables israéliens se sont enfermés dans une impasse intérieure et extérieure que seule une authentique coopération avec les Palestiniens permettrait de surmonter, analyse l’historien Jean-Pierre Filiu dans sa chronique au « Monde ».
DÉCRYPTAGE - Les deux principaux candidats à l’élection présidentielle brésilienne, dont le premier tour est prévu dimanche, défendent des conceptions diamétralement opposées de la diplomatie.
ANALYSE - Le président sortant, Luiz Inacio Lula da Silva, et son adversaire Flavio Bolsonaro, fils de l’ancien président Jair Bolsonaro, sont au coude-à-coude à la veille du premier tour.
La première mission de ce groupe, baptisé «unité super intelligence», sera de s’assurer que les États-Unis «(restent) en tête (dans la course à la) super intelligence».
From online-gambling rings in eSwatini to SIM swapping in Kenya and cybercrime networks in Zambia, a wave of cross-border fraud is drawing African governments and China into closer security cooperation. China hosted East African security ministers and police chiefs in Lianyungang, Jiangsu province, on September 10 for talks on terrorism, kidnapping, online fraud and other cross-border threats. China’s public security minister, Wang Xiaohong, said Beijing would strengthen law-enforcement...
The US is set to deploy one of its signature anti-ship missile systems to the Japanese island closest to Taiwan, an unprecedented move that comes as tensions in the region between Beijing and Tokyo continue to simmer. The ground-based US uncrewed missile platform known as the Navy-Marine Expeditionary Ship Interdiction System (NMESIS) will be deployed on Yonaguni Island in Japan’s Okinawa prefecture during biennial joint exercises this month, according to the regional bureau of the Japanese...
Chinese troops have taken part in a mass multinational exercise in Russia featuring new anti-drone and ground robot systems – drills that Russian state media said “applied lessons” from the Ukraine war. The troops were among more than 47,000 military personnel involved in the Tsentr-2026 – or Centre-2026 – drills in the central western Chelyabinsk region from Monday until Saturday. The Russian Ministry of Defence said the strategic command-and-staff exercise applied combat lessons from the...
US president tells a rally in Ohio that he believes there will be a 'big surprise' in the upcoming elections.
Yemen’s government forces claim to have killed hundreds of Houthi rebels as they attempt to retake lost territory.
Smit Machchhar habló con el primer ministro israelí, Benjamin Netanyahu, y dio nuevos detalles de cómo se produjo el ataque. Emiratos Árabes Unidos confirmó que Hamam Al-Hammami lo golpeó con un hacha.
El presidente tiene 3 puntos frente a su rival, lo que garantizaría el balotaje En la eventual segunda vuelta la ventaja del mandatario se reduce a solo un punto, 47% a 46%. Fuerte preocupación por la abstención.
O Departamento de Estado argumenta que os diplomatas ignoraram uma ordem para abandonar o país. Ainda, Netanyahu convidou o piloto que evitou o ataque ao avião da Flydubai a visitar Israel.
Des dizaines de membres de groupes d’extrême droite, faisant le salut nazi, se sont rassemblés samedi soir dans le centre de Madrid, où certains ont tenté de rejoindre la place où campent des militants pour le droit au logement, ont constaté des journalistes de l’AFP et des médias locaux. La police a été déployée en […] The post Espagne: des militants d’extrême droite font le salut nazi près d’un campement pour le droit au logement appeared first on Hespress Français - Actualités du Maroc .
Des soldats israéliens ont soutenu des colons, qui se sont emparés samedi d’oliveraies palestiniennes, et plusieurs blessés ont été signalés à travers la Cisjordanie occupée, ont indiqué des témoins et des secouristes. Octobre marque le début de la récolte pour les Palestiniens, dont beaucoup considèrent les oliviers comme un symbole culturel. La saison de cette […] The post Cisjordanie : des soldats israéliens accusés d’avoir facilité l’accès de colons à des oliveraies palestiniennes appeared first on Hespress Français - Actualités du Maroc .
Le bureau politique de l’Union constitutionnelle (UC) a décidé, à l’unanimité de ses membres, de mandater le secrétaire général du parti, Mohamed Joudar, pour conduire les consultations avec la Cheffe du gouvernement désignée et chargée de former le nouvel Exécutif, Fatima Ezzahra El Mansouri. Le bureau politique a également décidé d’accorder au secrétaire général les […] The post Mohamed Joudar mandaté pour conduire les négociations de l’Union constitutionnelle appeared first on Hespress Français - Actualités du Maroc .
Air traffic audio indicates the aircraft may have been "coming in blind" amid a storm.
Faced with a new Moscow policy designed to force people to abandon Kyiv and other cities, the Ukrainian president says he will double down on attacking Russian oil reserves.
La crisis de la memoria se ha convertido en el cuello de botella de la era de la IA también en la culpable de que la toda tecnología de consumo esté mucho más cara o de la extinción de los móviles chollo . Y cuando digo todo, no exagero: desde las consolas (que históricamente van abaratándose con el paso de los años ) hasta los coches . Y en este escenario en el que nos va tocar pagar más y a todos y a todas, hay gente que sale ganando. El ejemplo más claro es NVIDIA, pero en general los fabricantes de componentes viven días de vino y rosas y sino, que se lo digan a Micron . La empresa…
Ukrainian President Volodymyr Zelensky has asked Donald Trump to sanction the Russian and Chinese companies building Russia’s answer to Starlink, the Financial Times reported. He has raised it with Trump several times, including at a recent meeting in New York. Ukrainian news agency UNN cited those details from the FT report. A network for the front line The […] This story continues at The Next Web
Much of the worry about AI is that it will erode how well we write. Australian oral historian Shirleene Robinson thinks the bigger loss may be our ability to listen. She made the case in an opinion column for The Guardian. “Listening to different views and entering into different worlds is integral to our humanity,” she […] This story continues at The Next Web
A federal judge ruled that a sheriff’s deputy violated a woman’s Fourth Amendment rights when using Flock to search for her license plate without a warrant.
The CEO of Amazon Web Services tried to push back against widespread suspicion of data centers.
By his own admission, David Robinson is “something of a cliché”: an employee at a leading AI company who issues a dire warning while resigning from their job.
Capcom's Pragmata might be all about the horrors of AI, but in practice the studio doesn't seem so down on the tech. During the Capcom Open Conference RE: 2026 programmer Satoshi Ishida gave a presentation with the mouthful of a title: "The Outlook and Future of the REX Project, Further Evolving the RE Engine for […]
It’s not even October yet and Amazon is already offering some Prime Big Deal Day discounts on its own hardware, along with plenty of other popular products. It’s all to hype up October Prime Day, which starts October 6th at 3AM ET and lasts through 3AM ET on the 8th if you’re on the East […]
Kakul Srivastava is the CEO of Splice, the sample platform countless producers rely on for one-shots and melodic loops. Samples pulled from the service have found their way into massive hits like Lisa's "Money" and "Espresso" by Sabrina Carpenter. (The original samples are here and here, for the curious.) Before that, Kakul held executive roles […]
"...we were making history."
The devices continue to show noticeable benefits for users in various real-world tasks.
Cut the power, and the machine stops. That was part of the motivation behind a four-year effort to map all the proteins in the mitochondria—often called the powerhouse of the cell—of the parasites that cause sleeping sickness, giardiasis, leishmaniasis and babesiosis, diseases that together affect nearly a billion people every year.
Tau is a protein that occurs naturally in the brain. It is essential for proper neuron development and for how neurons communicate with each other. The same protein, however, when misshapen or misfolded, can act as a driver of neurodegenerative diseases. Abnormal buildup of tau is a hallmark of Alzheimer's disease, and scientists have also found an association between misfolded tau and more than 20 neurodegenerative diseases.
Scientists have identified an enzyme that may act as a natural defense against the worsening of fatty liver disease, which affects an estimated 100 million Americans. The enzyme, called UBE2N, helps liver cells clear away damaged mitochondria and break down fat, potentially preventing the inflammation, scarring, and cell damage associated with the more dangerous condition MASH.
The essential amino acid leucine can boost cellular energy production by protecting key proteins on mitochondria from being destroyed. The discovery reveals a new connection between nutrition and metabolism that could eventually lead to new approaches for metabolic disorders and cancer.
Scientists have linked a gut bacterial compound called ImP to greater Alzheimer’s risk, harmful brain protein buildup, and faster cognitive decline. The finding raises the possibility that reducing ImP in the blood could one day help slow or prevent dementia.
Aging Cell, Volume 25, Issue 10, October 2026.
Aging Cell, Volume 25, Issue 10, October 2026.
Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
Hepatitis B virus (HBV)-infected cells release hepatitis B surface antigen (HBsAg)-rich subviral particles (SVPs) in large excess over infectious virions. SVPs bind antibodies against HBsAg (anti-HBs), including neutralizing antibodies, but the physical products of antibody capture in human blood are uncharacterized. Here we used cryo-electron tomography (cryo-ET) to image HBsAg-enriched serum fr…
Estrogen receptor (ESR1) fusions are recurrent drivers of endocrine-resistant breast cancer, yet their mechanisms of action remain poorly understood. Here, we show that ESR1-e6 fusion proteins, including ESR1-DAB2, ESR1-SOX9, and ESR1-YAP1, assemble into nuclear condensates across multiple cell types. Sequence analysis reveals that these fusions combine chromatin-targeting domains with increased …
Folate is co-administered with fluoropyrimidines in colorectal cancer to potentiate thymidylate synthase inhibition, yet its therapeutic effects are paradoxically inconsistent across disease and treatment settings. Here we show that one-carbon metabolism remodels epithelial identity before treatment and thereby alters fluoropyrimidine response. Folate restoration shifted colorectal cancer cells a…
Protein homeostasis, or proteostasis, is essential for cellular health, and its disruption contributes to cancer, aging, and neurodegenerative disease. Proteostasis is maintained largely by two intracellular degradation systems: the ubiquitin proteasome system (UPS) and the autophagy lysosomal pathway (ALP). Here, we combine pulse stable isotope labeling by amino acids in cell culture (pSILAC) wi…
Neuroinflammation drives neurodegeneration and cognitive decline in aging, but the signals that spread this inflammation across the CNS remain unclear. Here, we show in mice that advanced age and experimental autoimmune encephalomyelitis (EAE) both result in elevated cytosolic mtDNA in microglia, which stimulates the production and export of cGAMP from these cells. Meanwhile, ENPP1, the dominant …
Heart failure (HF) affects approximately 6.2 million people in the United States, with a 5-year mortality exceeding 50%. Bradyarrhythmia, a known complication in HF due to sinoatrial node (SAN) dysfunction (SAND), increases morbidity and mortality of HF patients. Insights into the mechanistic underpinnings of SAND in HF could therefore uncover vital therapeutic targets to improve clinical outcome…
Clinical applications of gene editors including CRISPR-Cas9 are limited by the cell-type specificity and tissue penetrance of current in vivo delivery options. Cell-mediated gene editor delivery could overcome these obstacles. To date, systems utilizing immortalized cell lines have demonstrated gene editor delivery in vitro. Because T cells traffic throughout the organism and engage in intercellu…
Microtubules, composed of - and {beta}-tubulin polymers, are essential components of the eukaryotic cytoskeleton. They maintain cellular shape and structural integrity and play critical roles in cell division and in intracellular vesicular transport. In Plasmodium, the parasite that causes malaria, nuclear replication during the liver stage is among the fastest known in eukaryotic cells and relie…
Despite the success of immune checkpoint blockade in cancer therapy, overcoming the immunosuppressive tumor microenvironment remains a major barrier to durable responses. Here, we introduce cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4)-targeting chimeras (cTACs), a class of synthetic molecules that harness CTLA-4-mediated trans-endocytosis (TE) for targeted protein degradation across cellu…