Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-10-09 · biorxiv
· doi:10.1101/2025.10.02.679855
Weitzel, A. M.; Orchard, P.; Evans, C.; Manickam, N.; Treutelaar, M. K.; Britton, S. L.; Koch, L. G.; Li, J. Z.; Parker, S. C. J.; Burant, C. F.
Cardiorespiratory fitness (CRF) is a heritable trait associated with improved metabolic health and longevity. Integrating 546 transcriptomic and epigenomic profiles from skeletal muscle of 128 genetically heterogeneous rats selectively bred for high and low running capacity (HCR and LCR), a model that mirrors CRF-associated traits in humans, we identify a distributed enhancer architecture underly…
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bioRxiv (preprint)
· 2026-10-09 · biorxiv
· doi:10.64898/2026.10.08.757664
Ellis, S. J.; Angelopoulou, E.; Gandhi, K.; van Wolfswinkel, M.; Schmautz, L.; Oyarzun, I.; Nowosadtko, S.; Fischer, I.; Schwartz, V.; Griss, J. J.
In eutherian females, the choice of which X chromosome gets embryonically inactivated is thought to be random. Somatic tissues are thus assumed to comprise cells with a 50:50 ratio of maternal:paternal X active. However, a phenomenon known as X-skewing has been observed, wherein tissue composition shifts to be dominated by cells expressing one X or the other. On a gross level, such X-skewing is p…
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bioRxiv (preprint)
· 2026-10-09 · biorxiv
· doi:10.64898/2026.10.08.757667
Wells, B. L.; Filiberti, A. J.; Stanford, D. R.; Pham, K. D.; Walton, D. A.; Plafker, S. M.; Freeman, W. M.; Chucair-Elliott, A. J.
Purpose: Age is the leading factor for age-related macular degeneration (AMD), in which retinal pigmented epithelium (RPE) atrophy is a hallmark. The nuclear factor-erythroid 2-related factor 2 (Nrf2), a major anti-stress transcription factor, decreases in AMD, suggesting bioenergetic stress interacts with age during AMD pathogenesis. We profiled visual function and gene expression of the retina …
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Biomarker research
· 2026 Oct 9 · pubmed
· doi:10.1186/s40364-026-01006-x
Tien TY, Chang CY, Wu YJ, Lin CF
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Journal of cannabis research
· 2026 Oct 9 · pubmed
· doi:10.1186/s42238-026-00515-8
Draghmeh K, Gupta P, Yaggi H, D'Souza DC
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BMC public health
· 2026 Oct 9 · pubmed
· doi:10.1186/s12889-026-29518-z
Ibrahim HS, Raslan EI, Elsebaie EH
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Reproductive sciences (Thousand Oaks, Calif.)
· 2026 Oct 9 · pubmed
· doi:10.1007/s43032-026-02217-1
Xu C, Xu Y, Qingcao, Luo G
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Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie
· 2026 Oct 9 · pubmed
· doi:10.1111/jbg.70082
Pinto LFB, Visser C, Rocha AO, Alves JS
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Nature immunology
· 2026 Oct 9 · pubmed
· doi:10.1038/s41590-026-02702-4
Wang Y, Tian Q, Hao Y, Yao W
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GeroScience
· 2026 Oct 9 · pubmed
· doi:10.1007/s11357-026-02588-y
Nesci S, Algieri C
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Nature cell biology
· 2026 Oct 9 · pubmed
· doi:10.1038/s41556-026-02076-7
Bishop CL, Engin F, Han JJ, Krizhanovsky V
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EMBO molecular medicine
· 2026 Oct 9 · pubmed
· doi:10.1038/s44321-026-00525-2
Blackburn J, Nicholson JG, Gomez-Corral L, Xue J
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Journal of biomaterials applications
· 2026 Oct 9 · pubmed
· doi:10.1177/08853282261490031
Liu Y, Xu H, Hu J, Wang X
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Journal of materials chemistry. B
· 2026 Oct 9 · pubmed
· doi:10.1039/d6tb01410k
Yang Y, Liu Y, Cui Y, Jia W
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Asia-Pacific journal of clinical oncology
· 2026 Oct 9 · pubmed
· doi:10.1111/ajco.70207
Hayne D, Sengupta S, Zhang AY, Oliveira N