Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-10-23 · biorxiv
· doi:10.64898/2026.04.01.715811
Gouirand, N.; Ibrahimi, M.; Valotteau, C.; Lecouffe, B.; Le Bivic, A.; Massey Harroche, D.; Rico, F.; Merkel, M.; Delacour, D.; Bazellieres, E.
Epithelial tissue integrity and remodelling rely on mechanical coupling between cytoskeletal organization and adhesion complexes, but their orchestration in three-dimensional (3D) epithelia remains unresolved. Here, we introduced a non-invasive strategy to locally probe forces within 3D epithelial tissues. We engineered elastic polyacrylamide (PAAm) microbeads with cell-like size and mechanical p…
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bioRxiv (preprint)
· 2026-10-23 · biorxiv
· doi:10.64898/2026.10.21.760713
Held, M.; Partington, W.; Waring, T.; Dev, A.; Isherwood, L.; Boulton, B.; Sharma, P.; Herbert, R.; Kudoh, T.; Corbett, A. D.; Burton, R. A. B.
Analysing cardiac motion from label free imaging can be difficult, especially when recordings vary in quality or show complex movement. We developed a Python-based pipeline that automatically measures beat rate, contraction, speed from transmitted light timelapse data. The workflow runs in a Jupyter notebook and uses straightforward steps that can be followed easily, making the analysis accessibl…
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bioRxiv (preprint)
· 2026-10-23 · biorxiv
· doi:10.64898/2026.10.18.759616
Craparotta, I.; Barbera, M. C.; Cassanmagnago, G. A.; Salvatore, A. C.; Sallemi, A.; Guarrera, L.; Vallerga, A.; Bolis, M.
Throughout life, somatic cells must preserve their identity while retaining the capacity to adapt. How this balance shifts with ageing and rejuvenation remains unclear. Here we identify miR-29 as a central point of convergence between the transcriptional programmes of physiological ageing and two routes to rejuvenation: induced reprogramming and the natural reset of early development. miR-29 rise…
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bioRxiv (preprint)
· 2026-10-23 · biorxiv
· doi:10.64898/2026.10.22.760917
Fauver, O.; Hennig, G.; Sackheim, A.; Walters, B.; Barba, R.; Sonawane, R.; Bidlack, C.; Majumdar, D.; Trebak, M.; Nelson, M. T.; Freeman, K.
Ca2+ is both the signal that spreads injury information through the endothelium and the trigger for phospholipid scrambling that makes a membrane procoagulant. How a blood vessel can disseminate the first without broadcasting the second is unknown. Here, we combine single-cell laser injury in endothelial monolayers with imaging of intact mesenteric vessels in vitro and intravital Ca2+ imaging in …
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bioRxiv (preprint)
· 2026-10-23 · biorxiv
· doi:10.64898/2026.10.20.760390
Reardon-Lochbaum, C. A.; Cadinu, P.; Zhang, H.; Cantor, A. B.; Moffitt, J. R.
Hematopoietic stem cells (HSCs) reside in specialized bone marrow microenvironments, termed niches, which regulate self-renewal and differentiation through local support programs. Although multiple anatomically distinct niches with unique cellular compositions have been described, it remains unclear to what degree these niches differentially shape HSC fate. In parallel, hematopoietic output is mo…
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Sheng wu gong cheng xue bao = Chinese journal of biotechnology
· 2026 Oct 25 · pubmed
· doi:10.13345/j.cjb.260422
Ma J, Yang H, Wang X, Zhang Y
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Advanced materials (Deerfield Beach, Fla.)
· 2026 Oct 24 · pubmed
· doi:10.1002/adma.75503
Wang S, Wei Z, Wang Y, Wang S
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ACS biomaterials science & engineering
· 2026 Oct 24 · pubmed
· doi:10.1021/acsbiomaterials.6c01439
Wang Y, Liang N, Cai B, Jiang S
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Journal of the European Academy of Dermatology and Venereology : JEADV
· 2026 Oct 24 · pubmed
· doi:10.1111/jdv.70814
Tran HTT, Jing FZ, Le DV, Shrestha R
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Journal of Alzheimer's disease : JAD
· 2026 Oct 23 · pubmed
· doi:10.1177/13872877261500490
Chuang TC, Liang CK, Chou MY, Chan YH
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Journal of Alzheimer's disease : JAD
· 2026 Oct 23 · pubmed
· doi:10.1177/13872877261501439
Tian D, Shi T, Xu S, Lan J
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Journal of Alzheimer's disease : JAD
· 2026 Oct 23 · pubmed
· doi:10.1177/13872877261499243
Duboisdindien G, Durieux N, Kieu M, Cattini J
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Journal of Alzheimer's disease : JAD
· 2026 Oct 23 · pubmed
· doi:10.1177/13872877261497928
Duboisdindien G, Durieux N, Kieu M, Cattini J
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The New phytologist
· 2026 Oct 23 · pubmed
· doi:10.1111/nph.71670
Brandt D, Vilchez AC, Eirich J, Heinkow P
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Molecular biomedicine
· 2026 Oct 23 · pubmed
· doi:10.1186/s43556-026-00631-0
Xiao J, Li Y, Xie Y, Chen Y