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Los técnicos y la Guardia Civil intentan aclarar si la orden que recibió el AVE de avanzar a marcha normal tras la caída del sistema LZB fue un fallo puntual o se aplica de forma habitual
Los antecedentes de Angrois, Spanair, el Metro de Valencia y Adamuz auguran que la investigación se prolongará durante años
PP, Vox, Junts y PNV pedirán responsabilidades políticas ya y el ministro y el Gobierno esgrimirán que en otros accidentes no se dieron tantas explicaciones
Vox y otros grupos extremistas se lanzan en las redes y en la calle a insultar y criminalizar al Gobierno
Las compañías sustituyen la alta velocidad por reuniones telemáticas o el avión, que crece en todos los corr edores afectados
Un ingeniero participante en la programación del sistema de seguridad LZB del tramo Madrid-Sevilla sugiere que oscilaciones en la red podrían haber causado la desconexión del sistema.
Aznar soñó con unir Madrid en AVE con las capitales de provincia en menos de cuatro horas y la alta velocidad se ha llevado 15 veces más dinero que los trenes convencionales
La renovación en los últimos años va más allá de la cúpula y provoca malestar
Hours later Russian authorities said its app was also hacked, with fake warnings sent inside the country.
A rare humanitarian ceasefire allowed civilians to evacuate the Russian-occupied city of Oleshky.
The move by Haley Stevens, who lost out on the Democratic Senate nomination to Abdul El-Sayed, was called a "despicable betrayal" by one top Democrat.
British prime minister has now agreed to structured dialogue on reparatory justice but issue remains off formal Chogm agenda British officials reportedly insisted that discussions of reparations for slavery should not be on the agenda of the Commonwealth leaders’ summit in Antigua and Barbuda – and even warned that Andy Burnham would not attend the meeting if the subject was formally included, according to a leading Caribbean political figure. Ralph Gonsalves, a former prime minister of St Vincent and the Grenadines and a senior figure in the reparatory justice movement Repair Campaign,…
A truce has cooled the trade conflict, but neither country has done anything to limit the outbreak of new hostilities Donald Trump ’s trade wars have largely fallen off the headlines. Fears of new tariffs flare up from time to time when the US president goes off the rails – for instance, threatening to end US trade with countries with which it has a deficit unless the Federal Reserve cuts interest rates. But the sense that the world’s two largest economies are plowing ahead into an overt economic conflagration has taken a back seat to other, more salient fears, about Trump ending American…
Attorneys for an immigrant rights group on Saturday filed court papers revealing that their analysis found more than 40% of the people on the list do not appear in the state's voter file.
The aircraft had departed Austin-Bergstrom International Airport in Texas and was headed to the Bahamas, according to the Federal Aviation Administration.
La guerre en Iran et l’envolée du coût de la vie, malgré les promesses du président des Etats-Unis de juguler l’inflation et de ne plus engager son pays dans une aventure militaire extérieure, suscitent de fortes interrogations dans le camp républicain.
Outre-Rhin, le virage stratégique de l’armée en faveur d’un réarmement de sa marine a favorisé l’émergence de deux « champions » nationaux de la construction de navires de guerre, TKMS et Rheinmetall, à l’offensive à l’international.
Donald Trump a conclu, dimanche, ses déplacements de campagne par un rassemblement dans l’Iowa puis dans le Kansas, à deux jours de la clôture du scrutin. Le président américain avait déclaré, plus tôt dans la journée, qu’il pourrait devenir « Monsieur Veto » si les démocrates remportaient la majorité au Congrès à l’issue de ces élections.
DÉCRYPTAGE - Neuf ans après avoir promis de faire reculer les extrêmes, le président de la République voit une partie non négligeable de sa base lui échapper au profit du RN.
RÉCIT - La députée européenne, nièce de Marine Le Pen, ancienne députée FN, taille au forceps sa place dans l’orbite de la campagne présidentielle de sa tante, malgré un net refroidissement de ses relations avec Jordan Bardella.
Invitée du Grand Jury (RTL-Public Sénat-Ouest-France-M6) dimanche, l’essayiste et journaliste a précisé que les parrainages provenaient surtout de «maires femmes» attachées au «renouvellement de la classe politique».
Joshua Cooper Ramo is chairman and CEO of Sornay, an investment and advisory firm. Previously he was CEO of Kissinger Associates. Ramo is the author of the new book Darwin’s Lock: America, China and the Shared Future of Nations. His 2004 analysis of “the Beijing consensus” contrasted the Western and Chinese economic development models. He is the author of two New York Times bestselling books and now lives in Shanghai with his family. For other interviews in the Open Questions series, click...
Tuesday’s US midterm election is both hugely consequential and not so consequential even as the world waits to see the American voters’ verdict on Donald Trump’s presidency – and the impact that verdict will have on his temperament, plans and possible petulant response, analysts and former government officials said. On the one hand, an expected strong showing by opposition Democrats could bring more Congressional scrutiny over some of the most unconventional, maximalist and disruptive policies...
Joshua Cooper Ramo is chairman and CEO of Sornay, an investment and advisory firm. Previously he was CEO of Kissinger Associates. Ramo is the author of the new book Darwin’s Lock: America, China and the Shared Future of Nations. His 2004 analysis of “the Beijing consensus” contrasted the Western and Chinese economic development models. He is the author of two New York Times best-selling books and now lives in Shanghai with his family. For other interviews in the Open Questions series, click...
Iliana Iotova has won Bulgaria’s presidential runoff, becoming the country’s first elected female president.
Alger a annoncé, fin octobre, un déploiement de troupes au Niger, une première historique qui intervient après le dégel des relations avec le Mali. Ecarté de l’arène sahélienne au début des années 2020, Alger orchestre son retour pour contrer l’influence des Emirats arabes unis, du Maroc et de la Libye du maréchal Haftar.
Michigan Democrat Abdul El-Sayed's former opponent in the U.S. Senate primary, Haley Stevens, stunned party officials Sunday by endorsing Republican Mike Rogers after Democratic tensions boiled over days before the election that could determine the balance of power on Capitol Hill.
A business jet carrying nine people nosedived into a South Florida neighbourhood on Sunday and erupted into a giant fireball that appeared to just miss homes before crashing near a busy roadway. All passengers on board were killed, U.S. Transportation Secretary Sean Duffy said.
Parents say they feel betrayed by a decision to shut down a historic Southern Highlands primary school, with more than 1,600 people signing a petition to keep it open.
From fuel to food and a day at the football, Americans are feeling the burden of the rising cost of living. It's the only issue on the mind of many voters as they prepare to cast their ballot in the US midterm elections.
La mayoría de misiones no tripuladas comparten un mismo hándicap: las muestras o los datos deben enviarse a la Tierra para su análisis. Esto es algo que se está solucionando poco a poco. Ya existen rovers dotados con laboratorios internos que realizan todo tipo de pruebas in situ. Sin embargo, con el procesado informático la cosa cambia. Los datos deben procesarse en nuestro planeta, con una gran dependencia del ancho de banda. Para solucionarlo, la compañía HPE ha desarrollado Spaceborne Computer-4, un sistema de computación de alto rendimiento diseñado para funcionar directamente en la…
La privacidad en Windows 11 recibirá una de sus mejoras más importantes de los últimos años. Microsoft comenzó a probar nuevos controles que permitirán gestionar de forma individual el acceso de las aplicaciones de escritorio a la cámara, micrófono y ubicación. Esto es similar a lo que vemos en el móvil y ya existe en […] Seguir leyendo: Windows 11 por fin te dirá qué aplicaciones pueden verte, escucharte y rastrearte
Instagram is paying some YouTubers to bring their long videos across. It has offered select creators $50,000 to $500,000 to post long-form work to Features, its new 90-minute format. Sydney Bradley and Lucia Moses reported for Business Insider, citing people familiar with the deals. The deals are not exclusive. Instagram wants creators to post their […] This story continues at The Next Web
Hubble has no engine of its own, and it is slowly sinking. NASA now wants companies to say how they could lift the 36-year-old telescope higher, service it, or steer it down safely, the agency said on Friday. The request for information went out on 29 October, and responses are due by 30 November. NASA’s […] This story continues at The Next Web
Five stories worth your time from our extended colleagues at CIO, Computerworld, Macworld, and PCWorld.
Data centers are deeply unpopular. But what if we called them something else?
On Equity, we discuss why tech CEO statements can seem so tone deaf.
Jackery announced a new portable power station that uses the safer and longer-lasting lithium iron phosphate (LFP) batteries the company first introduced in 2023. But what makes the new Explorer 100D stand out is that it's Jackery's smallest power station to date, measuring only 4.6 by 3.4 by 3.4 inches and weighing just 1.87 pounds. […]
Gravity is a cruel mistress, slowly dragging the famed telescope ever closer to its ultimate demise with every day. Hubble is in no immediate danger of burning up in the Earth's atmosphere, but its time will run out in the early to mid 2030s unless its orbit is boosted. So NASA is taking proposals from […]
While more cities are canceling their contracts with Flock Safety, just as many are discovering how difficult that can be in some instances. Plymouth, Minnesota's city council voted to terminate its contract with Flock in September, but failed to respond to the city's request. For over a month, the cameras remained up, and the city […]
A recent scroll through social media got me thinking about trust. About half my feed was filled with AI slop that astute users would call out as being machine-generated, often to the embarrassment of the rube who unknowingly spread it and sometimes to the delight of the poster who shared it deliberately because they found it amusing or useful for sowing confusion. Remember the good old days of GPT-3 when we could ask the chatbot anything and it would almost instantly and very confidently spit back a plausible but false answer? That’s when the word “hallucination” as applied to AI answers…
The reliable assessment of metabolic dysfunction-associated steatotic liver disease (MASLD) is crucial for determining the stage of the disease, initiating appropriate treatments and monitoring the course of therapy. To date, a liver biopsy has often been necessary for this purpose. In this invasive procedure, a tissue sample is taken and examined.
Researchers at The Hong Kong Polytechnic University (PolyU) have developed an imaging biomarker, the Tumour Heterogeneity Index (THI), which enables noninvasive assessment of breast cancer patients' response to AKT inhibitors before treatment, helping clinicians identify patients most likely to benefit from therapy. The study found that patients with a high THI achieved an estimated pathological complete response (pCR) rate of 56.1%, significantly higher than that of patients with a low THI. The technology could help patients receive the most appropriate treatment at an earlier stage, reduce…
When a patient arrives in the emergency department with severe abdominal pain, every minute counts. Researchers at the University of Colorado Anschutz School of Medicine are investigating ways to streamline the work of radiologists and make it more efficient. They also aim to quickly identify patients who may need urgent surgery and speed up the path to treatment.
A massive study of nearly 486,000 adults found that regularly drinking tea was associated with an 11% lower risk of heart and blood vessel diseases. The lowest risk was linked to drinking roughly six to eight cups per day, with black tea showing more consistent benefits than green tea.
A UCLA study found that long-term exposure to a common pesticide was linked to more than 2.5 times the risk of Parkinson's disease. Scientists also uncovered how the chemical damages brain cells and identified a promising way to protect them.
New England Journal of Medicine, Ahead of Print.
New England Journal of Medicine, Ahead of Print.
Shares of gene editing therapy companies mostly surged this past week on two growth catalysts: Data readouts at the European Society of Gene and Cell Therapy’s 33rd ESGCT Annual Congress, and the FDA's new draft guidance for personalized gene therapies. The post StockWatch: Gene Editing Shares Jump on ESGCT Data, FDA Draft Guidance appeared first on GEN - Genetic Engineering and Biotechnology News .
Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
Mitochondrial dysfunction is a central feature of Down syndrome (DS), yet how trisomy 21 affects brain bioenergetics across scales--from gene transcription to cellular function to whole-brain metabolism--remains poorly understood. Here, we use the Dp16(1)Yey/+ (abbreviated Dp16) DS mouse model, which carries ~115 triplicated gene orthologs of human chromosome 21, to address this major knowledge g…
Centrosomes organize microtubules, coordinate ciliogenesis, and support accurate cell division. At the mature mother centriole, distal and subdistal appendages confer specialized functions in ciliary docking, microtubule organization, and intracellular trafficking. Nuclear distribution element 1 (NDE1) is a centrosome-associated regulator of dynein-dependent processes and ciliogenesis, but its na…
Blood-based DNA methylation is widely used as a molecular surrogate for traits ranging from circulating protein and metabolite levels to biological aging, but whether the CpGs driving these models reflect genuine gene regulation or statistical convenience is unresolved. Training elastic-net models using the expression of 77 T cell genes across 333 matched T-cell enriched blood samples, we show th…
Quantifying individual protein behavior in living mammalian tissues remains challenging. Here we introduce intravital single-molecule microscopy (iSiMM), an imaging and analysis framework that combines instant structured illumination microscopy guided tissue navigation with highly inclined and laminated optical sheet illumination. In live mice, iSiMM enables single-emitter detection and tracking …