Últimas 48 h · PubMed · Europe PMC · bioRxiv · incluye Aging-US y Rejuvenation Research vía PubMed
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bioRxiv (preprint)
· 2026-11-02 · biorxiv
· doi:10.64898/2026.10.28.762545
Trim, W. V.; Diakova, M.; Sonnett, M.; Petrova, K.; Zhang, B.; Oh, S.; Donne, R.; McEwen, C.; Salmon, H.; Gadi, A.; Shavlakadze, T.; Chouchani, E. T.; Glass, D. J.; Kirschner, M. W. W.
Aging alters tissue architecture and metabolism in spatially heterogeneous ways, yet the connections between these measurable structural and compositional phenotypes and underlying molecular changes are largely unknown. Here, we introduce NORIGAMI (NoRI-Guided AI for Multimodal Integration), a pipeline combining Normalized Raman Imaging (NoRI), deep learning, quantitative morphology, deep proteom…
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bioRxiv (preprint)
· 2026-11-02 · biorxiv
· doi:10.64898/2026.10.30.761943
Ferrando-Soler, M.; Garrido, G.; Andreu-Carbo, M.; Ascunde, A.; Rubio, J.; Benages, A.; Izquierdo-Villalba, I.; Mayor, F.; Ribas, C.; Enrich, C.; Rentero, C.; Beninca, C.; Aragay, A. M.
Lysosomes and mitochondria are highly dynamic organelles whose coordinated interactions are essential for cellular homeostasis, while their dysfunction contributes to numerous human diseases. Here, we identify the mitochondrial outer membrane protein Fis1 and the RabGAPs TBC1D15 and TBC1D17 as novel interacting partners of the heterotrimeric G protein -subunit Gq. Using mitochondrial proteomics, …
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bioRxiv (preprint)
· 2026-11-02 · biorxiv
· doi:10.64898/2026.10.30.762933
Ugulini, S.; Hardy, D. B.; Dhanvantari, S.
Glucagon secretion by pancreatic cells is regulated by nutrient, paracrine, and neural inputs, and emerging evidence suggests that the islet endocannabinoid system (ECS) may also regulate -cell function. While phytocannabinoids such as cannabidiol (CBD) have been shown to interact with the ECS, and negatively regulate insulin secretion from pancreatic {beta} cells, whether CBD alters cell func…
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Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
· 2026 Nov 4 · pubmed
· doi:10.1097/DSS.0000000000005421
Butterwick KJ, Palm MD, Shafer D
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Molecular & cellular proteomics : MCP
· 2026 Nov 3 · pubmed
· doi:10.1016/j.mcpro.2026.101701
Xiao Q, Xiang W, Song F, Wang N
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Journal of fish biology
· 2026 Nov 3 · pubmed
· doi:10.1111/jfb.70710
Teixeira-Leite CV, Vaz-Dos-Santos AM, Santana FM, Santander-Neto J
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JMIR aging
· 2026 Nov 3 · pubmed
· doi:10.2196/98665
Tang D, Sheehan KJ, Conroy S, Goubar A
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Dermatology and therapy
· 2026 Nov 3 · pubmed
· doi:10.1007/s13555-026-01944-2
Lephart ED, Leverett J, Kong R, Draelos ZD
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The Journal of the American Academy of Orthopaedic Surgeons
· 2026 Nov 3 · pubmed
· doi:10.5435/JAAOS-D-25-01643
Valiquette A, Seidl A
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Journal of aging and health
· 2026 Nov 3 · pubmed
· doi:10.1177/08982643261502730
Sun R, Zimmer Z
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Biochimica et biophysica acta. Reviews on cancer
· 2026 Nov 3 · pubmed
· doi:10.1016/j.bbcan.2026.189746
Palumbo P
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Ageing research reviews
· 2026 Nov 3 · pubmed
· doi:10.1016/j.arr.2026.103438
Deng X, Wang L, Luo M, Wu J
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Ageing research reviews
· 2026 Nov 3 · pubmed
· doi:10.1016/j.arr.2026.103437
Montenegro CF, Murach KA, Chambers TL
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Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
· 2026 Nov 3 · pubmed
· doi:10.1097/DSS.0000000000005442
Ticknor I, Given KM, Hausauer A
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Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
· 2026 Nov 3 · pubmed
· doi:10.1097/DSS.0000000000005396
Fabi S, Liu C, Carruthers J